Patient Resources

What is Progressive Supranuclear Palsy (PSP)?

Progressive supranuclear palsy (PSP) is a rare brain disorder that affects approximately 25,000 people in the United States and 50,000 people in the European Union. PSP results from the health of nerve cells worsening over time (degenerating) in the frontal and temporal lobes of the brain. PSP can lead to symptoms including:

• Unsteady balance
• Unexplained falls
• Stiffness and awkwardness in gait
• Forgetfulness
• Personality changes (e.g. irritability)
• Blurry vision
• Weakness of vertical eye movement
• Slurred speech
• Trouble swallowing

PSP is slightly more prevalent in men than women, and symptoms begin to appear between the ages 45 and 75. Early symptoms are similar to those of other neurological disorders, such as Parkinson’s disease and Alzheimer’s disease.

There are currently no approved treatments for PSP. If you are concerned that you may have symptoms related to PSP, see your physician or neurologist for more information on the disorder and potential clinical trials.

Research

Allon Therapeutics is conducting a clinical trial in PSP. To find out more about this study, please visit ClinicalTrials.gov.

Other Resources

For additional information on support groups and education surrounding PSP, please contact or visit the following organizations’ websites: